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Updated: Jun 4, 2025

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在mTORC1抑制后,TFEB在三阴性乳腺癌细胞中触发了矩阵降解和入侵程序

David Remy1, Sandra Antoine-Bally1, Sophie de Toqueville1

  • 1Institut Curie, CNRS UMR 144, PSL University, 75005 Paris, France.

Developmental cell
|December 27, 2024
PubMed
概括

在三阴性乳腺癌 (TNBC) 中抑制PI3K/AKT/mTOR通路可促进基质降解和侵入性. 这一意想不到的结果表明,对乳腺癌治疗的mTOR抑制剂进行重新评估.

关键词:
在MT1-MMP中使用.美国联邦税务法 (TFEB)细胞外矩阵是细胞外矩阵.侵袭opodiaodia的时间.这是一种mTOR抑制剂.在 mTORC1 的情况下,mTORC1 是来自患者的异种移植.三重阴性乳腺癌是什么瘤的入侵 瘤的入侵

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