通过短信传递的大麻使用障碍治疗的年轻人:一项大型随机临床试验
Michael J Mason1, J Douglas Coatsworth1, Nathaniel R Riggs2
1Center for Behavioral Health Research, College of Social Work, University of Tennessee, United States of America.
Journal of substance use and addiction treatment
|December 27, 2024
概括
同行网络咨询文本 (PNC-txt) 通过提高动机和减少伤害的技能,间接减少了年轻成年人的大麻使用. 这种文本交付的干预措施对治疗大麻使用障碍 (CUD) 有希望.
科学领域:
- 成 药物 药物 药物 药物
- 数字健康干预措施 数字健康干预措施
- 行为心理学 行为心理学
背景情况:
- 大麻使用障碍 (CUD) 提出了重大治疗挑战,特别是在不成比例地受到影响的年轻成年人中.
- 开发可扩展和可访问的治疗方法至关重要,文本交付的干预措施有可能增加覆盖范围和隐私.
- 了解治疗有效性的临床机制对于优化干预措施至关重要.
研究的目的:
- 为了评估通过短信传递干预措施的有效性,同行网络咨询文本 (PNC-txt),用于治疗年轻成年人的CUD.
- 检查假设的因果途径,包括动机和行为策略的变化,通过PNC-txt可以减少大麻使用.
- 评估CUD的文本交付治疗的可扩展性和吸收潜力.
主要方法:
- 一项随机临床试验涉及1078名美国年轻成年人被诊断患有CUD.
- 参与者被分配到为期4周的PNC-txt干预或等待列表对照组.
- 在6个月的时间内进行了后续评估,以测量大麻使用和介导变量.
主要成果:
- 在治疗组和对照组之间没有观察到PNC-txt对大麻使用的显著直接影响.
- 在假设的调解者身上发现了显著的治疗效应:增加了愿意改变和采用保护性行为策略的准备.
- 隐性变化得分调度建模表明,1个月后变化准备和行为策略的改善预测了6个月后大麻使用量的减少.
结论:
- PNC-txt通过提高参与者的动力和教导减少危害策略,证明了在减少大麻使用方面的间接有效性.
- 这些发现表明,针对变化准备和保护性行为策略是CUD治疗的可行的临床机制.
- 像PNC-txt这样的文本交付干预措施显示出作为在年轻成年人中解决CUD的可访问和可扩展的选择的希望.
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