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Updated: Jun 4, 2025

Assessing Mitochondrial Function in Sciatic Nerve by High-Resolution Respirometry
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Assessing Mitochondrial Function in Sciatic Nerve by High-Resolution Respirometry

Published on: May 5, 2022

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核呼吸因子-1 (NRF1) 诱导驱动线粒体生物发生,并减弱粉样β诱导的线粒体功能障碍和神经毒性

Matteo Massaro1, Gherardo Baudo1, Hyunho Lee1

  • 1Department of Nanomedicine, Houston Methodist Research Institute, Houston, TX, 77030, USA.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
|December 27, 2024
PubMed
概括

在阿尔茨海默病 (AD) 中,抑制核呼吸因子-1 (NRF1) 的神经元与粉样β (Aβ) 诱导的线粒体功能障碍作斗争. 这种方法增强了线粒体生物发生和功能,最终保护神经元免受Aβ相关损伤.

关键词:
阿尔茨海默氏症的疾病是阿尔茨海默氏症.粉样蛋白β是什么 粉样蛋白β是什么线粒体生物发生是线粒体生物发生.线粒体功能障碍 线粒体功能障碍核呼吸因子-1 (NRF1) 是一种核呼吸因子.

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