心率可变性参数表明COVID-19患者的自主语调发生变化
Gabriel Gruionu1, Md Aktaruzzaman1, Anita Gupta2
1Krannert Cardiovascular Research Center, Division of Cardiovascular Medicine, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Scientific reports
|December 27, 2024
概括
COVID-19显著扰乱了自主调节,由心率变化 (HRV) 降低和同情主导来表明,类似于心血管疾病患者. 年轻,女性和非白人个体表现出更大的自主功能障碍.
科学领域:
- 心脏病学 心脏病学
- 自主神经系统研究 自主神经系统研究
- 传染病并发症 传染病并发症
背景情况:
- COVID-19与长期的心血管问题有关.
- 心率变化 (HRV) 反映了自主神经系统 (ANS) 的平衡 (交感/副交感).
- 以前的研究表明,HRV可以预测COVID-19的结果,但人口统计学影响需要全面分析.
研究的目的:
- 在住院COVID-19患者中评估交感性 (SNS),副交感性 (PNS) 和心律调节的平衡.
- 将COVID-19患者的HRV与健康志愿者和心血管疾病 (CVD) 患者进行比较.
- 调查年龄,体重指数 (BMI),性别和种族对COVID-19患者HRV的影响.
主要方法:
- 50名COVID-19患者,31名健康志愿者和51名心血管疾病患者的心电图记录.
- 计算14个HRV参数:时间域,频域,非线性和规律度指标.
- 对包括年龄,BMI,性别和种族在内的人口因素的分析.
主要成果:
- 与健康对照组相比,COVID-19和心血管疾病患者的时间域HRV (SDNN,RMSSD) 显著减少.
- 无论是COVID-19还是CVD群体,低频 (LF) 功率增加和高频 (HF) 功率下降.
- 在COVID-19患者中,非线性HRV参数SD1显著降低,表明自主调节发生了改变. 年轻,女性和非白人个体表现出更明显的自主功能障碍.
结论:
- COVID-19患者表现出显著的HRV变化,这表明自主功能障碍与阴道音调降低和交感主导.
- 在COVID-19中,这些HRV变化与在患有严重心血管并发症的患者中观察到的变化相似.
- 尽管心率可能更高,但COVID-19显著破坏了自主调节,特别是在具有特定人口风险因素的患者中,尽管心率可能更高.
更多相关视频
05:48Autonomic Function Following Concussion in Youth Athletes: An Exploration of Heart Rate Variability Using 24-hour Recording Methodology
Published on: September 21, 2018
10.0K
06:24Examining Changes in HRV and Emotion Following Artmaking with Three Different Art Materials
Published on: January 11, 2020
6.0K
相关概念视频
Factors Influencing Heart Rate
2.0K
The heart rate, or pulse rate, is a vital indicator of cardiovascular health. It reflects the number of times the heart beats per minute. Various physiological and environmental factors influence heart rate, increasing or decreasing cardiac output. Understanding these factors is crucial for assessing heart function and identifying potential health issues.
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
2.0K
Regulation of Heart Rates
1.2K
The regulation of heart rate is a complex process controlled by the autonomic nervous system (ANS), hormonal influences, and intrinsic cardiac mechanisms. The ANS has two main components: the sympathetic nervous system (SNS) and the parasympathetic nervous system (PNS).
The SNS increases heart rate through the release of norepinephrine and epinephrine, which act on beta-1 adrenergic receptors in the heart. This action increases the rate of depolarization in the sinoatrial (SA) node, the...
The SNS increases heart rate through the release of norepinephrine and epinephrine, which act on beta-1 adrenergic receptors in the heart. This action increases the rate of depolarization in the sinoatrial (SA) node, the...
1.2K
Regulation of Pulse
1.1K
Pulse regulation involves physiological mechanisms that ensure adequate blood flow throughout the body. The heartbeat, regulated by the autonomic nervous system, is influenced by hormonal balance, physical activity, and emotional state.
1.1K
Decreased pulse rate
515
Bradycardia is a medical condition in which the heart rate is slower than normal. It occurs when the heart's natural pacemaker, the sinus node, generates slower electrical impulses than the standard rhythm. In adults, bradycardia is diagnosed when the pulse rate falls below 60 beats per minute, indicating a deviation from the normal heart rate range.
There are specific risk factors that can elevate the likelihood of developing bradycardia. Advanced age is a significant factor, with...
There are specific risk factors that can elevate the likelihood of developing bradycardia. Advanced age is a significant factor, with...
515
Disturbances in Heart Rhythm
699
Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
699
Increased pulse rate
620
Tachycardia is a condition marked by an abnormally fast or irregular heart rate, surpassing the typical resting rate. In adults, tachycardia is characterized by a pulse rate ranging from 100 to 180 beats per minute. The increased heart rate can result in inadequate blood flow to various body parts, ultimately diminishing the oxygen supply to organs and tissues.
Many factors can elevate the risk of developing tachycardia. These include advanced age, a family history of arrhythmias, and an...
Many factors can elevate the risk of developing tachycardia. These include advanced age, a family history of arrhythmias, and an...
620
