糖尿病介导心脏代谢指数和结石之间的关系:一个横截面研究
Guicao Yin1, Wentao Zhang1, Jialong Zhang1
1Department of Urology, The Affiliated Hospital of Jiangsu University, Jiangsu University, Zhengjiang, 212000, Jiangsu Province, China.
Scientific reports
|December 27, 2024
概括
升高的心脏代谢指数 (CMI) 与美国成年人的结石风险更高有关. 糖尿病起着调解作用,这表明血糖控制是预防结石的关键.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 心脏病学 心脏病学
- 代谢健康 代谢健康
背景情况:
- 糖尿病是结石的已知危险因素之一.
- 心脏代谢指数 (CMI) 评估心血管和代谢健康.
- 关于CMI与结石相关的证据有限.
研究的目的:
- 调查美国成年人中CMI和结石之间的关联.
- 确定糖尿病是否调解了CMI和结石之间的关系.
主要方法:
- 分析国家健康和营养检查调查 (NHANES) 数据 (2007-2018).
- 包括10,609名受试者 (972人患有结石).
- 统计方法:多因素逻辑回归,子组分析,RCS曲线,值效应和调解分析.
主要成果:
- 在CMI和结石之间发现了显著的积极关联 (OR 1.29,95% CI [1.16,1.44]).
- 观察到CMI和结石之间存在非线性正相关性.
- 糖尿病调解了CMI和结石之间的关系的15.3%.
结论:
- 升高的CMI与结石风险增加有关.
- 糖尿病在这种关联中扮演着重要的调解角色.
- 保持较低的CMI和管理血糖控制对于预防结石很重要.
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