Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Oxygen Transport in the Blood01:27

Oxygen Transport in the Blood

2.2K
Hemoglobin (Hb) is a crucial molecule in the human body, consisting of four polypeptide chains, each bound to an iron-containing heme group. This unique structure enables hemoglobin to bind to oxygen, with each molecule capable of combining with four molecules of oxygen, leading to rapid and reversible oxygen loading. When fully loaded with oxygen, it is called oxyhemoglobin, while hemoglobin that has released oxygen is called reduced hemoglobin or deoxyhemoglobin. As hemoglobin binds oxygen,...
2.2K
Hemoglobin01:24

Hemoglobin

3.0K
Hemoglobin is a globular protein made up of four subunits. Two of these subunits are alpha chains, and the other two are beta chains. Each subunit contains a molecule of heme, which has an iron atom and can bind to oxygen. When an oxygen molecule binds to one heme group, it changes the shape of hemoglobin, making it easier for the other heme groups to bind oxygen as well.
When all four heme groups are bound to oxygen, the resulting molecule is called oxyhemoglobin. As a result, arterial blood...
3.0K
Factors Affecting Respiration01:24

Factors Affecting Respiration

3.9K
Respiration is a crucial physiological function involving exchanging oxygen (O2) and carbon dioxide (CO2) between an organism and its environment. Various factors can impact this essential process:
3.9K
Factors Affecting Erythropoiesis01:24

Factors Affecting Erythropoiesis

2.9K
The cardiovascular system regulates the number of erythrocytes in the bloodstream to ensure optimal oxygen transport. It also prevents over-proliferation of these cells, which helps to maintain blood viscosity and flow rate.
Several factors influence the erythrocyte production rate, with tissue oxygen level being among the most critical. Intense exercise or high altitudes can cause tissue hypoxia, which triggers the kidneys to release more erythropoietin (EPO) into the bloodstream.
EPO then...
2.9K
Disorders of Erythrocytes01:27

Disorders of Erythrocytes

713
Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
713
Hypoxia01:23

Hypoxia

837
Hypoxia is a medical condition characterized by an inadequate oxygen supply to body tissues. It typically manifests as a bluish discoloration of the skin and mucosae, especially in fair-skinned individuals, when hemoglobin (Hb) saturation drops below 75%.
Types of Hypoxia
There are four primary types of hypoxia, each resulting from a different cause:
1. Anemic hypoxia: This type occurs due to insufficient oxygen delivery caused by a lack of red blood cells (RBCs) or RBCs with abnormal or...
837

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Immunonutrition Decreases Postoperative Complications in Gastrointestinal Cancer-A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Advances in nutrition (Bethesda, Md.)·2026
Same author

Impact of Breast Augmentation, Reduction, and Nipple Repair on Breastfeeding Success: A Systematic Review and Meta-analysis.

Aesthetic surgery journal·2026
Same author

Clinical practice patterns in the pre-endoscopic management of individuals presenting with acute upper gastrointestinal bleeding: results of an international survey.

Therapeutic advances in gastroenterology·2026
Same author

High-Intensity Training Increases Osteocalcin Levels: A Meta-Analysis of Effects of Exercise on Bone Remodeling biomarkers.

Sports medicine - open·2026
Same author

Antitumor Activity of Cannabinoids and Their Interaction with Chemotherapy: A Systematic Review and Meta-Analysis of Preclinical Evidence.

Pharmaceuticals (Basel, Switzerland)·2026
Same author

One out of four patients with pancreatic cancer experience psychological symptoms: A systematic review and meta-analysis.

PloS one·2026
Same journal

Peripheral B-cell receptor repertoire predicts immune-related adverse events following immune checkpoint inhibitor therapy in advanced renal cell carcinoma.

Scientific reports·2026
Same journal

Effects of black soldier fly (Hermetia illucens L.) larvae zoocompost on the mineral element content of blue honeysuckle berries.

Scientific reports·2026
Same journal

Investigation on absorption refrigeration performance of R1243zf with imidazolium ionic liquid as the working pairs.

Scientific reports·2026
Same journal

DeepTriage-CN: integrating clinical text with vital signs for emergency department admission prediction in an aging population.

Scientific reports·2026
Same journal

Gold nanoparticles as dual-action antiviral agents: disruption of SARS-CoV-2 viral envelopes and RNA integrity.

Scientific reports·2026
Same journal

Comparison of capillary microsampling and venous blood for multi-pathogen serosurveillance.

Scientific reports·2026
查看所有相关文章

相关实验视频

Updated: May 8, 2025

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
07:24

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy

1.7K

血红蛋白下降预测不良结果比贫血的严重程度更好.

Brigitta Teutsch1,2,3, Zsolt Abonyi Tóth4,5, Orsolya Ferencz4

  • 1Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary. teutschbrigitta@gmail.com.

Scientific reports
|December 28, 2024
PubMed
概括
此摘要是机器生成的。

在胃肠道出血 (GIB) 中,较高的相对血红蛋白降低 (ΔHb%) 显著增加了不良结果,甚至超过了典型的输血值. 这突显了DHb%作为GIB患者管理中的关键风险因素.

关键词:
德尔塔血红蛋白是什么意思降低了血红蛋白的水平.具有限制性的限制性输血 输血 输血是指输血.

更多相关视频

Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management
05:35

Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management

Published on: January 19, 2024

670
Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry
08:23

Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry

Published on: November 5, 2019

9.7K

相关实验视频

Last Updated: May 8, 2025

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
07:24

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy

1.7K
Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management
05:35

Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management

Published on: January 19, 2024

670
Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry
08:23

Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry

Published on: November 5, 2019

9.7K

科学领域:

  • 胃肠病学 胃肠病学
  • 血液学 血液学 血液学
  • 临床医学 临床医学

背景情况:

  • 胃肠道出血 (GIB) 患者对急性失血的耐受性有所不同.
  • 在GIB中评估患者的结果通常依赖于绝对血红蛋白水平.
  • 血红蛋白*降低率对GIB结局的影响尚未完全理解.

研究的目的:

  • 调查相对血红蛋白降低 (ΔHb%) 对GIB患者临床结果的影响.
  • 为了确定 ΔHb% 是否是 GIB 中不良事件的显著预测因素,独立于血红蛋白水平的最低值.

主要方法:

  • 来自匈牙利GIB注册表 (2019-2022) 的数据分析.
  • 根据最低血红蛋白 (nadirHb) 和 ΔHb% 的值,患者被分为两组.
  • 主要结局:医院内出血相关死亡率和紧急干预的组合.

主要成果:

  • 较高的ΔHb%始终与复合终点的概率增加有关,无论Hb.
  • 30-40%的ΔHb%降低到80-90g/L的Hb最低水平显示出类似的不良结果的可能性,与0-10%的ΔHb%降低到较低的Hb最低水平 (70-80g/L或60-70g/L).
  • 增加的ΔHb%与不良结果相关,即使nadirHb超过了推的输血值.

结论:

  • 相对血红蛋白降低 (ΔHb%) 是GIB患者不良结果的重要风险因素.
  • 在GIB的临床决策中,应该与nadirHb和输血值一起考虑ΔHb%.
  • 未来对GIB输血策略的随机对照试验应将ΔHb%作为关键变量.