低于最佳的饮食模式与年轻成年期加速的生物衰老有关:一项对双胞胎的研究
Suvi Ravi1, Anna Kankaanpää1, Leonie H Bogl2
1Faculty of Sport and Health Sciences, Gerontology Research Center, University of Jyväskylä, 40014 Jyväskylä, Finland.
Clinical nutrition (Edinburgh, Scotland)
|December 28, 2024
概括
不健康的饮食加快了年轻人的生物衰老. 相反,植物性和均衡的饮食促进衰老的缓慢,遗传学在这种关联中发挥着作用.
科学领域:
- 营养科学 营养科学
- 表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.
- 双胞胎研究 双胞胎研究
背景情况:
- 低于最佳的饮食模式与增加的发病率和死亡率有关.
- 表观遗传钟提供了一种评估生物年龄和寿命的方法,即使在年轻人身上也是如此.
- 了解饮食对生物衰老的影响对于预防性健康策略至关重要.
研究的目的:
- 研究不同饮食模式与年轻成年双胞胎生物衰老之间的关联.
- 区分遗传学和共享环境对饮食相关生物衰老的影响.
主要方法:
- 利用了来自FinnTwin12研究的数据 (n=826个双胞胎,年龄21-25岁).
- 使用食物频率问卷和潜伏类分析评估饮食模式.
- 通过表观遗传钟 (GrimAge,DunedinPACE) 测量生物衰老,并使用线性回归和双胞胎内对分析.
主要成果:
- 确定了六种饮食模式,包括"植物性"",健康意识"",平衡平均"和"高快餐,低F&V".
- 植物性,健康意识和平衡平均饮食与高快餐,低F&V相比,与更慢的灰色年龄加速有关.
- 双胞胎内对分析表明,遗传学,而不是共享环境,部分介导了饮食-生物衰老联系.
结论:
- 富含快餐,加工肉类和含糖饮料,低含水果/蔬菜的饮食加快了年轻人的生物衰老.
- 研究结果强调了早期饮食选择对长期健康的重要性.
- 在评估饮食对衰老的影响时,应考虑遗传倾向和生活方式因素.
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