在切除瘤的头骨切割中输血:发生率,危险因素和结果
Namrah Aziz1, Usama Waqar1, Muhammad Murtaza Bukhari1
1Medical College, Aga Khan University, Karachi, Pakistan.
概括
输血在神经外科中常见,用于瘤切除,但会增加并发症风险. 接受输血的患者面临更高的死亡率,重大发病率和更长的住院时间.
科学领域:
- 神经外科和麻醉学
- 输血医学 输血医学
- 手术结果研究研究.
背景情况:
- 血液输血 (BT) 经常在神经外科手术过程中是必要的,例如骨切除瘤,以控制贫血,缺血性脑损伤和出血等风险.
- 然而,术后输血可能会增加手术后不良并发症的风险.
研究的目的:
- 为了调查进行内瘤切除的头骨切除术的患者输血的发生率.
- 为了确定与这种患者群体中需要输血相关的因素.
- 确定在这些程序期间接受输血的结果和并发症.
主要方法:
- 一项回顾性队列研究利用了来自国家外科质量改进计划 (NSQIP) 数据库的数据.
- 包括在内的是2005年至2021年期间接受瘤切除选择性骨切除术的成年患者.
- 采用多变量逻辑回归分析,在30天内识别BT和相关的术后并发症的预测因素.
主要成果:
- 在40883名患者中,3.65%需要输血.
- 与增加BT概率相关的因素包括年龄> 60,女性性别,体重不足BMI,ASA 3-4类,糖尿病,COPD,手术前贫血,出血障碍和脑膜瘤指示.
- 接受BT治疗的患者在长时间使用呼吸机,尿路感染,未计划的重新手术,长时间住院,重大发病率和全因死亡率上有显著更高的几率.
结论:
- 预测骨切除患者需要输血的关键因素是晚年,女性性别,低BMI,严重的并发症 (ASA 3-4,COPD),贫血,出血障碍和先前输血.
- 在这个队列中,输血与不良结果的风险增加有关,包括主要的发病率,死亡率,长时间住院和重新手术.
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