在早产发病率的季节性变化
C MacBride1, L Creswell1, E McNamee1
1Department of Obstetrics and Gynecology, The Coombe Hospital, Dublin, Ireland.
European journal of obstetrics, gynecology, and reproductive biology
|December 28, 2024
概括
季节性受孕和分娩影响早产率. 冬季怀孕显示出较低的早产 (PTB) 风险,而冬季分娩显示出较高的PTB率在爱尔兰队列中. 需要进一步的研究.
科学领域:
- 产科和妇科 产科和妇科
- 围产期流行病学 围产期流行病学
- 公共卫生 公共卫生
背景情况:
- 怀孕和分娩的季节性变化可能会影响怀孕的结果.
- 过早分娩 (PTB) 仍然是复杂的病因因素的一个重大问题.
- 了解季节性影响可以为PTB的预防策略提供信息.
研究的目的:
- 调查怀孕季节和出生季节与早产发病率 (PTB) 之间的关联.
- 分析季节性模式对新生儿结局的影响.
- 确定与PTB季节性变化相关的潜在可修改的风险因素.
主要方法:
- 在爱尔兰都柏林的一个中心 (2013-2022) 进行了单独生育的回顾性队列研究.
- 对综合数据库的分析,以确定按受孕季节和出生季节分层的PTB发病率.
- 报告和分层的新生儿结局基于PTB或到期出生.
主要成果:
- 对76,988名新生儿的分析显示,PTB发病率的季节性变化很大.
- 与其他季节相比,冬季 (12月至2月) 的怀孕与PTB率显著降低 (5.4%).
- 与其他季节相比,冬季 (12月至2月) 的出生显示出明显更高的PTB率 (6.2%).
结论:
- 在爱尔兰队伍中观察到早产发病率的明显季节性变化.
- 冬季怀孕与PTB的发病率降低相关,而冬季分娩与发病率增加有关.
- 需要进一步的研究来阐明PTB的特定季节性风险因素,这些风险因素可能是可以修改的.
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