随机对照试验协议分析不同含量耐性粉的米对慢性便秘的影响
Yiping Zhao1, Fanyu Zhao1, Qian Liu1
1Innovation Center of Nursing Research, Nursing Key Laboratory of Sichuan Province, West China Hospital, and West China School of Nursing, Sichuan University, PO Box No.37, Guo Xue Street, Chengdu, 610041, Sichuan, PR China.
Scientific reports
|December 29, 2024
概括
这项研究调查了不同耐性粉水平的米如何影响老年人慢性便秘. 这些发现可以提供改善老年人肠道健康的饮食策略.
科学领域:
- 老年学是一门学科.
- 胃肠病学 胃肠病学
- 营养科学 营养科学
背景情况:
- 全球人口老龄化导致老年人慢性便秘的患病率增加.
- 饮食干预措施,特别是耐性粉,通过调节肠道微生物群来控制便秘有希望.
- 有限的研究存在于不同类型的米,在耐性粉含量上有所不同,对老年人便秘的具体影响.
研究的目的:
- 评估各种抗性粉度的米在老年人中缓解慢性便秘的有效性.
- 为老年人群管理便秘提供基于证据的饮食建议.
主要方法:
- 这是一项为期24周的双盲,双臂随机对照试验,涉及长期护理机构中患有慢性便秘的老年人.
- 参与者被随机分配为食用米A (11-20%耐性粉) 或米B (0.1-0.5%耐性粉),卡路里和其他饮食成分标准化.
- 通过韦克斯纳问卷评估的结果包括生活质量,抑郁,焦虑和睡眠质量在6,12和24周.
主要成果:
- 主要结局:通过韦克斯纳问卷测量便秘症状的严重程度.
- 二次结果:生活质量的变化,抑郁,焦虑和睡眠质量.
- 这项研究是第一个随机对照试验,调查了老年人抗米粉含量和慢性便秘.
结论:
- 预计这项试验将提供关键的见解,了解特定的食大米类型在老年人慢性便秘管理中的作用.
- 结果将为为老龄化人口服务的医疗保健专业人员提供基于证据的便秘护理协议.
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