与对照组相比,COVID-19对后COVID患者心率变异性的影响
Aldair Darlan Santos-de-Araújo1, Daniela Bassi-Dibai2,3, Renan Shida Marinho4
1Cardiopulmonary Physiotherapy Laboratory, Physical Therapy Department, Universidade Federal de São Carlos, Rodovia Washington Luiz, São Carlos, SP, 13565-905, Brazil.
轻微的COVID-19在感染后的几个月中暂时影响心率变化 (HRV),特别是副交感调节. HRV的恢复受到自诊断以来的时间和年龄的影响,这表明一种暂时的自主神经系统效应.
科学领域:
- 心脏病学 心脏病学
- 自主神经系统研究 自主神经系统研究
- 传染病流行病学 传染病流行病学
背景情况:
- 轻微的COVID-19可以影响各种生理系统,包括自主神经系统.
- 心率变化 (HRV) 是自主神经系统功能的一个关键指标.
- 了解轻度COVID-19对HRV的长期影响对于患者的康复至关重要.
研究的目的:
- 为了研究轻度COVID-19在感染后的不同时间点对HRV的影响.
- 将轻度COVID-19病史的个体的HRV与健康的对照组进行比较.
- 确定影响轻度COVID-19后HRV恢复的因素.
主要方法:
- 横截面研究包括130个被分为对照组和三个COVID-19后组 (≤6周,2-6个月,7-12个月) 的个人.
- 对线性和非线性HRV指数的分析.
- 使用ANOVA或Kruskal-Wallis进行统计比较,并进行效果大小计算 (科恩的d或 η2). 线性回归模型被用来确定HRV参数的预测因素.
主要成果:
- 与对照人群相比,在轻度COVID-19后 ≤6个月的个体表现出降低的副交感调制.
- 感染后7-12个月的个体与感染后≤6个月的个体相比,表现出增加的副交感调制.
- 感染年龄和持续时间是HRV参数的重要预测因素,如RMSSD,SD1和SDNN. 压力是高频 (HF) 功率的预测因素.
结论:
- 轻微的COVID-19对自主神经系统有暂时的影响,主要影响感染后最初几个月的副交感调节.
- HRV的恢复受到自诊断以来的时间和个体年龄的影响.
- 这些发现强调了在COVID-19后恢复过程中监测自主功能的重要性.
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