根据前性队列研究,在儿科重症监护中,年龄特定的脆弱性和狂妄症的高患病率
AbdulRahman AlDaithan1,2, Naila Shaheen3,4, Eidah Alahmari3,5
1King Abdullah International Medical Research Center, Riyadh, Saudi Arabia. dr.a.aldaithan@gmail.com.
Scientific reports
|December 29, 2024
概括
儿科狂妄症在重症监护室很常见,几乎70%的儿童受到影响. 婴儿和有呼吸道问题的儿童是最脆弱的,阿片类药物使用是显著的危险因素.
科学领域:
- 儿科重症监护医药 儿科重症监护医药
- 神经精神病学是一种神经精神病学.
- 流行病学 流行病学
背景情况:
- 痴呆症对儿科重症监护室 (PICU) 的儿童产生重大影响,导致更长的住院时间和死亡率增加.
- 了解儿科狂妄症的负担和危险因素对于改善患者的治疗结果至关重要.
- 这项研究解决了关于重症儿童痴呆症的知识差距.
研究的目的:
- 调查三级 PICU 中痴呆症的流行率和特征.
- 为了确定儿童 Delirium 的风险因素和潜在的治疗目标.
- 分析 delirium 和临床结果在重症儿童之间的关联.
主要方法:
- 对890名进入PICU的儿童进行前性队列研究.
- 每12小时检查一次妄症,使用康奈尔儿童妄症评估 (CAPD).
- 对人口统计,并发症,药物,干预措施和临床结果的分析,以确定妄想症的关联.
主要成果:
- Delirium 的高患病率 (69.4%),婴儿不成比例地受到影响 (33.5% 的病例).
- 呼吸系统诊断 (78.6%) 与痴呆症显著相关;阿片类药物使用增加了45.2%的风险.
- 痴呆症与更长时间的ICU停留和所有20例死亡率有关; 97.6%的戒断症候群儿童患有痴呆症.
结论:
- 儿科 Delirium 在 PICU 中非常普遍,婴儿和那些有呼吸道诊断的人特别容易受到伤害.
- 吸食阿片类药物和戒断综合征是重症儿童妄的重要危险因素.
- 需要进一步的研究来开发针对性的干预措施,以预防和管理儿科 Delirium.
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