美国成年人口中饮食摄入量与湿疹之间的相关性
Qianjie Wu1, Zitao Guo2, Na Zhang3
1Wuxi Medical College, Jiangnan University, Wuxi, China.
Scientific reports
|December 29, 2024
概括
饮食中的摄入量显示了与成人湿疹患病率的反转U形相关性. 适度减少摄入量可能有利于湿疹发病率,因此需要进一步调查最佳水平.
科学领域:
- 皮肤病学 皮肤病学
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 湿疹是一种常见的慢性皮肤疾病,可能与饮食因素有关.
- 以前的研究探讨了摄入量在婴儿湿疹中的作用,但成人相关性仍未研究.
- 了解饮食对成人湿疹的影响对于公共健康至关重要.
研究的目的:
- 研究饮食摄入量与成年人 (≥18岁) 湿疹患病率之间的关联.
- 探索非线性关系,并确定摄入效应的潜在值.
主要方法:
- 从2005-2006年国家健康和营养检查调查 (NHANES) 中对4086名成年人的横截面分析.
- 通过24小时回忆评估饮食摄入量;通过过敏问卷确定湿疹患病率.
- 用于分析相关性和非线性关系的物流回归和受限制立方支线 (RCS) 模型.
主要成果:
- 在更高的饮食摄入量 (第三季度) 和发病率增加 (OR: 1.913,P=0.043) 之间发现了显著的关联.
- 限制立方线分析显示,饮食摄入量与湿疹患病率之间存在反转的U形相关性 (非线性P<0.05).
- 摄入量的增加与高湿疹患病率相关,低于7.089的对数摄入值 (OR:1.790,P=0.048).
结论:
- 饮食中的摄入量与成人湿疹患病率呈现出反转的U形关系.
- 适度减少摄入量可能有助于减少湿疹发病率.
- 需要进一步的前性研究来确认因果关系并确定预防湿疹的最佳摄入水平.
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