一个连锁调解模型揭示了老年人抑郁症和认知功能之间的关联
Penghao Fan1, Hongying Li1, Hongyan Xu1
1School of Humanities and Management, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Scientific reports
|December 29, 2024
概括
抑郁症显著影响老年人的认知功能. 社会活动和日常生活活动 (ADL) 发挥着关键的调解作用,通过复杂的途径影响认知健康.
科学领域:
- 老年学是一门学科.
- 认知神经科学 认知神经科学
- 公共卫生 公共卫生
背景情况:
- 抑郁症是老年人中普遍存在的问题,通常与认知能力下降同时发生.
- 了解介导抑郁症和认知功能之间的关系的因素对于开发有针对性的干预措施至关重要.
- 社会参与和执行日常活动的能力被认为是老年人福祉的重要决定因素.
研究的目的:
- 在老年人群中调查抑郁症,认知功能,社交活动和日常生活活动 (ADL) 之间的直接和间接关系.
- 检查社会活动和ADL在抑郁症和认知功能之间的关联中潜在的链中介效应.
- 量化直接,间接和连锁介导作用对老年人认知功能的贡献.
主要方法:
- 利用了来自中国健康与退休长度研究 (CHARLS) 第四阶段7547名老年参与者的数据.
- 使用相关性分析来评估抑郁症,认知功能,社交活动和ADL之间的相互关系.
- 应用Bootstrap方法来测试和验证链中介效应的意义.
主要成果:
- 抑郁症对老年人的认知功能的直接影响占总影响的36.85%.
- 通过社会活动和ADL的间接影响是显著的,分别占总影响的15.99%和44.64%.
- 观察到社交活动和ADL具有显著的链中介效应,对总效应贡献2.44%.
结论:
- 抑郁症对老年人的认知功能有相当大的直接影响.
- 社会活动和ADL是重要的调解者,部分解释了抑郁症如何影响认知健康.
- 这些发现突出了老年人群中心理健康,社会参与,功能能力和认知状态之间的复杂相互作用,表明了干预的途径.
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