盐水灌对骨水泥早期机械特性和微观结构的影响
Seyed Morteza Kazemi1, Alireza Mirahmadi1, Pooya Hosseini-Monfared1
1Bone, Joint and Related Tissues Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Scientific reports
|December 29, 2024
概括
在手术期间用盐水灌聚 (甲基甲酸盐) 骨水泥并没有显著影响其强度或微观结构. 然而,一个品牌在灌时显示强度降低,这表明需要仔细考虑这种冷却方法.
科学领域:
- 整形外科手术 整形外科手术
- 生物材料科学 生物材料科学
- 聚合物化学 聚合物化学
背景情况:
- 聚 (甲基甲酸) (PMMA) 骨水泥在聚合过程中产生大量的热量,在骨科植入物固定中存在风险.
- 用盐溶液灌已经被提出作为一种方法来冷却PMMA骨在手术期间.
研究的目的:
- 为了研究盐水灌 (正常和冷) 对两个PMMA骨水泥品牌的屈曲强度和微观结构的影响.
- 为了比较灌骨水泥标本与各种老化期后的非灌对照组.
主要方法:
- 两个PMMA骨水泥品牌 (Simplex P和FIX 1) 进行了测试.
- 标本被分为三个组:正常盐水灌 (25°C),冷盐水灌 (4°C) 和没有灌 (控制).
- 使用ISO 5833协议评估柔性强度,通过扫描电子显微镜 (SEM) 分析表面微观结构,在PBS中在37°C老化1小时,24小时和7天后.
主要成果:
- 盐水灌通常不会显著改变测试的PMMA骨的屈曲强度或表面微观结构.
- 显著的例外是长达24小时的Simplex P,在这种情况下,用正常和冷盐水灌导致曲强度明显降低,与对照组相比.
- 微观结构分析显示,两组之间没有显著差异.
结论:
- 使用盐水灌冷却PMMA骨质水泥在水泥化关节塑造过程中需要仔细考虑,因为可能对机械性能产生不良影响,如在Simplex P.中观察到的.
- 需要进一步的研究,以充分了解盐水灌对外科手术中的骨质水泥性能的影响.
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