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Updated: May 1, 2026

Evaluation of Zebrafish Kidney Function Using a Fluorescent Clearance Assay
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雷萨祖林染料是脏管状功能的体内传感器

Shirely Acosta Martinez1, Isaac Z Karel1, Josie A Silvaroli1

  • 1Division of Pharmaceutics and Pharmacology, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA.

Kidney international
|December 29, 2024
PubMed
概括

研究人员发现,染料resazurin可以检测脏管状功能障碍. 这种新方法比目前的测试更灵敏,即使膜过率正常,也可以识别问题.

关键词:
急性脏损伤急性脏损伤是什么球膜过率是指球膜的过率管状上皮细胞是管状上皮细胞.拉布多米溶解 (rhabdomyolysis) 是一种治疗方法.

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G-Protein Gated Ion Channels01:21

G-Protein Gated Ion Channels

GPCRs are primarily responsible for our sense of smell, taste, and vision.  The binding of a sensory stimulus activates GPCR to stimulate effector proteins, many of which are ion channels in the sensory organs. GPCRs modulate the opening and closing of the target ion channels either directly by binding them, or by releasing second messengers that activate these channels. As ions move across the membrane, the membrane potential is altered, which induces an appropriate response.
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