IL-10信号调节PRKN甲基化,并影响STAT3活动以驱动调节性巨细胞分化

Lihuan Wang1, Lingzhi Xu2, Shuo Song3

  • 1Department of Allergy Medicine & Pulmonary and Critical Care Medicine, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, China.

概括

抑制PRKN (E3无素蛋白联酶) 增加调节性巨细胞 (Mregs),抑制呼吸道过敏. 这一发现为免疫系统疾病提供了潜在的治疗策略.

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