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Updated: Jun 4, 2025

Non-invasive Assessment of the Efficacy of New Therapeutics for Intestinal Pathologies Using Serial Endoscopic Imaging of Live Mice
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提奥斯特普顿通过与活性氧物种相关的细胞内膜网膜应激抑制结肠直肠癌的进展

Zhexuan Li1, Juan Nie2, Runyu Zhou3

  • 1Yu-Yue Pathology Scientific Research Center, Chongqing 400039, PR China; Jinfeng Laboratory, Chongqing 400039, PR China.

Toxicology and applied pharmacology
|December 29, 2024
PubMed
概括

一种抗生素thiostrepton通过诱导细胞死亡和减少瘤生长来对抗结肠直肠癌. 它通过引起蛋白质毒性和ER压力来起作用,这一过程依赖于反应性氧物种 (ROS).

关键词:
结肠直肠癌是一种癌症.细胞内膜网膜应激压力蛋白质毒性压力是保护性毒性的.有反应性氧物种的反应性氧物种.这里是Thiostrepton.

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