手握强度和体重指数在腹腔透析患者中表现出对皮症的良好预测价值
Hongyan Li1,2, Yuanhua Zheng3, Yuanyuan Zhang1,4
1School of Nursing, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Frontiers in nutrition
|December 30, 2024
概括
使用身体质量指数 (BMI) 和手握强度的新型诺莫格拉姆模型可以有效地预测经过腹腔透析 (PD) 的患者的肉症. 这些工具提供了一种简单且具有成本效益的方法,用于早期检测和治疗PD患者的肉类症.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 老年病的医生 老年病的医生
- 临床诊断 临床诊断 临床诊断
背景情况:
- 在腹腔透析 (PD) 患者中诊断萨科佩尼是具有挑战性的,因为复杂和昂贵的评估.
- 开发可访问的查工具对于管理这种人群中的肉症至关重要.
研究的目的:
- 开发和验证特定性别的诺莫格拉姆模型,用于预测PD患者的肉症.
- 为了更容易诊断,利用常规后续指标,如BMI和手握强度.
主要方法:
- 从两个中国医院招募了699名PD患者.
- 采用多变量逻辑回归来识别男性和女性肉类的预测因子.
- 使用启动重新抽样和ROC曲线分析构建和内部验证的诺莫格拉姆模型.
主要成果:
- 在中国PD患者中,肉类的患病率为13.92%.
- 手握强度和BMI被确定为两性独立预测因素.
- 诺米图模型显示出高的预测准确性 (男性AUC为0.924,女性AUC为0.936) 并且校准非常好.
结论:
- 结合BMI和手握强度的性别特异性诺莫格拉姆模型显示了在PD患者中 Sarcopenia 的强有力的预测性能.
- 这些模型提供了一种方便且经济的方法,用于在临床环境中早期检测和管理sarcopenia.
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