意大利边缘化社区的HBV和HCV检测结果,2019-2024年:前性研究
Monica Monti1, Teresita Caruso1,2, Alice Castellaccio3
1MASVE Interdepartmental Hepatology Center, Department of Experimental and Clinical Medicine, University of Florence, Center for Research and Innovation CRIA-MASVE, Firenze, Italy.
The Lancet regional health. Europe
|December 30, 2024
概括
查边缘化社区的乙型肝炎病毒 (HBV) 和乙型肝炎病毒 (HCV) 发现感染率更高. 成功地实现了与护理的联系,强调了有针对性的干预措施的重要性,以减少健康差异,并致力于消除HBV/HCV.
科学领域:
- 肝病学和传染性疾病.
- 公共卫生和流行病学.
- 健康差异研究 研究健康差异研究
背景情况:
- 边缘化人口面临着严重的健康不平等,影响着整体公共卫生结果.
- 世界卫生组织报告称,2022年有超过3.04亿人感染乙型肝炎病毒 (HBV) 或乙型肝炎C病毒 (HCV).
- 针对性查对于在脆弱群体中识别和管理隐藏的HBV/HCV感染至关重要.
研究的目的:
- 评估意大利托斯卡纳边缘化社区HBV和HCV感染的流行率.
- 评估现场查的有效性和随后与积极参与者的护理联系.
- 为减少HBV/HCV差异和实现全球消除目标的战略提供信息.
主要方法:
- 从2019年1月到2024年5月,手指刺伤血液测试被用于现场HBV/HCV查.
- 在非营利组织进行了选,目标是边缘化人口.
- 阳性参与者被转介到当地门诊诊所进行进一步的管理和治疗.
主要成果:
- 在4.4%的参与者中发现了乙型肝炎表面抗原 (HBsAg) 阳性,主要是男性和非意大利本地人.
- 在2.9%的参与者中观察到抗HCV阳性,与意大利国籍和较低的教育水平相关;静脉注射药物使用是关键风险因素.
- 在相当一部分HBV/HCV阳性患者中,成功地实现了连接和留在护理中的成功,而在病毒性HCV患者中,治疗成功率很高.
结论:
- 在这个边缘化的队列中,HBV/HCV的患病率超过了国家平均水平,这强调了有针对性的查的必要性.
- 地理来源和社会经济因素被确定为HBV/HCV感染的重要风险因素.
- 有效的查和关联到护理计划对于减少健康差异和朝着世界卫生组织2030年HBV/HCV消除目标迈进至关重要.
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