在2型糖尿病中阻塞性睡眠呼吸暂停的患病率和影响:一项描述性的横截面研究
Puneet Saxena1, Dharmendra Singh2, Yashpal Singh3
1Classified Specialist (Respiratory Medicine), Army Hospital (R&R), New Delhi, India.
Medical journal, Armed Forces India
|December 30, 2024
概括
阻塞性睡眠呼吸暂停 (OSA) 影响超过70%的印度2型糖尿病患者,即使是那些没有肥胖的人. 这种情况与更糟糕的糖尿病控制和增加的微血管并发症有关.
科学领域:
- 内分泌学 在内分泌学.
- 肺部病理学 肺部病理学
- 糖尿病学 糖尿病学
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 在2型糖尿病中很常见.
- 关于印度人口中OSA-糖尿病关系的研究有限.
研究的目的:
- 调查印度2型糖尿病患者的OSA患病率.
- 探索OSA与糖尿病控制,胰岛素抵抗和微血管并发症之间的关联.
主要方法:
- 一项横截面研究在24个月内招募了80名糖尿病患者.
- 透视视镜 (PSG) 诊断了OSA;血液样本评估了糖尿病控制和并发症.
主要成果:
- 在73.8%的患者中,OSA存在,不论BMI或腰围/部周长.
- 在OSA患者中,HbA1c和胰岛素耐药性较高.
- 微血管并发症 (神经病变,视网膜病变,DKD) 在OSA患者中更为普遍.
结论:
- 印度糖尿病患者的OSA患病率很高,独立于肥胖.
- 在糖尿病患者中,OSA与较差的血糖控制,增加的胰岛素抵抗,以及较高的微血管并发症风险有关.
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