平色素:来自印度东北部的临床病理学研究
Adahra P Beso1, Mary Z Chhangte2, Biswajit Dey3
1Pathology, State Cancer Institute, Gauhati Medical College and Hospital (GMCH), Guwahati, IND.
Cureus
|December 30, 2024
概括
平色素 (LPP) 呈现为持久的,无症状的,平淡灰色的色素,通常在阳光照射的区域. 组织病理学揭示了诸如黑色素失禁和Civatte体等关键特征,有助于诊断.
科学领域:
- 皮肤病学 皮肤病学
- 病理学 病理学 病理学
背景情况:
- 平色素 (LPP) 是一种不常见的平色素变体.
- 其特点是暗棕色到灰色色素斑的阴险发作,主要在阳光照射的区域和曲折.
- 主要报告在印度人,拉丁裔,美国人和中东人口中.
研究的目的:
- 为了记录Lichen planus pigmentosus (LPP) 的临床病理学特征.
主要方法:
- 一项为期五年的回顾性研究 (2017年1月至2021年12月) 分析了42名被诊断患有LPP的患者.
- 排除了带有黑色素,炎症后色素或无法获得的活检的病例.
- 审查了人口统计,临床和组织病理学数据;使用了H&E,马森三色和刚果红色污点.
主要成果:
- 该研究包括42名患者 (29名女性,13名男性),平均年龄为34.2岁.
- 最常见的部位:头部和部 (33.3%),上肢 (21.4%),背部 (19%).
- 组织病理学显示了正皮,表皮稀疏,黑色素失禁和Civatte体 (78.3%).
结论:
- 慢性皮肤炎是一种常见的色素障碍,具有持久的,无症状的,光滑灰色的色素.
- 关键的组织病理学发现包括脊髓炎,密集的皮肤淋巴细胞透,黑色素失禁和Civatte体.
- 临床病理学文档有助于理解和诊断LPP.
相关概念视频
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