低激素与术后结果之间的关联在经过尿道外前列腺手术的患者中
Jasmine S Lin1, Evan J Panken2, Sai Kumar3
1Urology, Cedars-Sinai Medical Center, Los Angeles, USA.
Cureus
|December 30, 2024
概括
经过前列腺手术的近一半男性的丸激素 (T) 低. 低T与180天再入院的风险更高有关,这表明T查可能对手术患者有益.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 内分泌学 在内分泌学.
- 老年医学 老年医学
背景情况:
- 低 (T) 与虚弱相关,并预测手术患者的恢复不佳.
- 低T对经过尿道外科手术的患者周围手术结果的影响还没有得到很好的描述.
研究的目的:
- 为了研究低T,虚弱和术后结果之间的关联,在接受过尿道切除前列腺 (TURP) 或前列腺激光光蒸发 (PVP) 的男性中.
主要方法:
- 对175名接受TURP或PVP的男性进行了回顾性审查,这些男性在手术前的丸激素水平.
- 低T定义为血清T<300 ng/dL.
- 低T和正常T组之间的临床特征,实验室值和脆弱性 (医院脆弱性风险评分) 的比较.
- 单变量和多变量分析评估了低T和30,90和180天再入院之间的关联.
主要成果:
- 49.1%的患者患有低T;这些患者年龄较大,术后停留时间较长.
- 低T患者的180天再入院率显著更高 (28%对13%,p=0.02).
- 低T并没有独立地与脆弱性相关,但手术前T与90日和180天的再入院有关.
结论:
- 低丸激素在接受过尿道前列腺手术的男性中普遍存在.
- 低T独立地与180天重入院的风险增加有关.
- 在这种患者群体中,低T的术前查可能具有预后价值,因此需要进一步调查治疗疗效.
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