在使用雌激素激素治疗的跨性别者中,雌激素度和幸福感
Ariel Ginger1, Sav Zwickl1, Lachlan M Angus1,2
1Trans Health Research Group, Department of Medicine (Austin Health), The University of Melbourne, Australia.
Transgender health
|December 30, 2024
概括
在接受女性化激素治疗的跨性别女性中,更高的雌激素水平与心理困扰或失调症没有临床联系. 推个性化治疗,需要进一步研究以获得最佳的治疗方案.
科学领域:
- 内分泌学 在内分泌学.
- 跨性别者健康 跨性别者健康
- 心理学 心理学 心理学
背景情况:
- 雌激素治疗女性化激素治疗的最佳雌激素度尚未确立.
- 一些跨性别人士寻求超生理性雌激素水平.
- 了解雌醇水平对心理健康和医疗风险的影响至关重要.
研究的目的:
- 检查雌激素度与跨性别女性心理痛苦,幸福感和性别障碍症之间的关联.
- 研究雌激素水平与与激素治疗相关的疾病风险之间的关系.
主要方法:
- 在澳大利亚进行了一项探索性在线横截面研究,对172名跨性别人士进行了雪球采样.
- 参与者年龄为16岁或以上,接受雌激素治疗.
- 雌激素度与心理困扰 (K10),幸福感 (PWI-A) 和性别障碍症的验证尺度相关.
主要成果:
- 雌二醇度的中位数为420 pmol/L.
- 在雌醇度与心理困扰,幸福感或性别障碍之间没有发现临床显著的关联.
- 虽然观察到K10和PWI-A得分的统计学意义上的变化与更高的雌激素,大小很小,并没有临床相关. 没有发现与血栓形成,中风或高血压的联系.
结论:
- 由于缺乏与心理结果的明确关联,建议对雌激醇激素治疗采取个性化的方法.
- 需要进一步的前性研究,采用更大的样本大小,以确定最佳的女性化激素治疗方案.
- 目前的研究结果表明,当前的雌醇水平不会显著影响该人口的心理痛苦或幸福感.
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