在疟疾中,急性功能衰竭与血栓缩性血栓细胞紫外线混:一个病例报告
Pinar Gurkaynak1, Nejla Yılmaz Gocen2, Ahmet Mert Yanık3
1Department of Infectious Diseases and Clinical Microbiology, Karabuk University Training and Research Hospital, Karabuk, Turkey.
Iranian journal of parasitology
|December 30, 2024
概括
严重的疟疾,包括脑性疟疾和急性损伤,可能被误诊. 及时诊断和管理Falciparum疟疾并发症对于患者的康复至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 热带医学 热带医学
- 腎臟病學 (nephrology) 是一種醫學.
背景情况:
- 疟疾的流行率有所增加,特别是在撒哈拉以南非洲,由COVID-19大流行中断所加剧.
- 严重的疟疾症状包括脑疟疾和急性损伤,往往需要密集护理和替代疗法.
- 区分严重的疟疾和其他条件,如血栓性血栓性缩性紫外线 (TTP) 可能是具有挑战性的,因为重叠的临床和实验室特征.
研究的目的:
- 报告一个严重的型疟疾病例与脑疟疾和急性损伤.
- 突出诊断挑战和考虑从特有地区的患者疟疾的重要性.
- 强调及时和适当管理疟疾引起的并发症的关键作用.
主要方法:
- 一份病例报告显示,一名来自得共和国的22岁男性患者出现了混乱和严重疾病的迹象.
- 临床评估,实验室检查,包括寄生虫检测和功能监测.
- 用口服阿尔特梅瑟+卢梅方特林治疗以及多次血液透析.
主要成果:
- 该患者被诊断患有严重的型疟疾,其特点是脑性疟疾,超寄生虫病 (15%),超白病和急性损伤.
- 最初的错误诊断被认为是由于与血栓性血栓性缺血性紫外线 (TTP) 的相似性.
- 患者在抗疟疾治疗24小时内出现临床改善,并在血液透析解决功能障碍后出院.
结论:
- 疟疾的延迟诊断可能发生在症状模仿微血管病性血液溶解性贫血症时.
- 严重疟疾的有效管理需要及时诊断,适当的抗疟疾治疗,以及对急性损伤等并发症的积极治疗.
- 这一案例凸显了在对表现为严重全身性疾病的患者和曾前往特有地区的旅行史的患者的差异诊断中考虑疟疾的重要性.
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