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Updated: May 7, 2025

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机器学习辅助工程 血红蛋白作为碳转移酶用于催化酶选择性烯酸环旋化

Hanqing Xie1, Kaifeng Liu1, Zhengqiang Li1

  • 1Key Laboratory of Molecular Enzymology and Engineering of Ministry of Education, School of Life Sciences, Jilin University, Changchun 130023, P. R. China.

JACS Au
|December 30, 2024
PubMed
概括

研究人员使用机器学习策略将玻璃血红蛋白 (VHb) 改造成碳转移酶. 这种VHb-WK突变体对烯酸环化产生了很高的酶选择性,证明了有效的蛋白质设计方法.

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