额头骨年结的血栓:对管理和结果的系统审查
Amber Cintosun1, David Belzile2, Maala Sooriyakanthan2
1Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
CJC open
|December 30, 2024
概括
在环化 (MAC) 上形成血栓是罕见的,但会增加血栓栓塞的风险. 大多数患有MAC血栓的患者使用抗凝药进行治疗,尽管有些人需要手术,并且可能发生持续的血栓或栓塞.
科学领域:
- 心脏病学 心脏病学
- 膜心脏疾病 膜心脏疾病
- 血栓形成的原因之一是血栓形成.
背景情况:
- 伴心环状化 (MAC) 是一种常见的退行性过程,影响伴心.
- 在MAC上形成血栓是一种罕见但显著的并发症,增加了血栓栓塞事件的风险.
- 目前对MAC血栓的结果和管理策略的了解有限.
研究的目的:
- 进行一项系统性审查,描述MAC上的血栓患者的管理和结果.
- 在这个患者群体中确定治疗策略和相关的临床事件.
主要方法:
- 在MEDLINE,Embase和Cochrane数据库中进行系统搜索.
- 包括在MAC上报告患有血栓的患者的研究,不包括那些先前进行了门干预或假肢的患者.
- 主要结局评估包括治疗,死亡率和血栓塞栓事件.
主要成果:
- 该审查包括了15项研究,包括22例病例;大多数患者是女性,出现中风,过渡性缺血事件或心肌梗塞.
- 大多数患者 (77%) 仅用抗凝药治疗;23%需要手术,通常用于复发性栓塞.
- 没有报告死亡率,但27%的患者经历了诊断后的血栓栓塞事件,23%的仅服用抗凝血剂的人患有持续性血栓.
结论:
- 呈现血栓栓塞事件的MAC患者需要对血栓进行心声回声评估.
- 虽然抗凝剂通常是足够的,但很大一部分患者需要手术干预.
- 持续性血栓和复发性栓塞是常见的,突出显示需要进一步研究最佳的长期管理.
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