在使用WATCHMAN FLX设备进行皮革左心室尾闭塞手术后,跨织物泄漏
Nicholas J C Bauer1,2, Abdullah F Alfawaz1,3,4, Lan-Chau Kha1,3
1Schulich Heart Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
CJC open
|December 30, 2024
概括
在左心房尾闭塞 (LAAO) 程序后,跨织物泄漏 (TFL) 是常见的,在27-52%的患者中发生. 与TFL相关的预测因素和显著的临床事件仍然不清楚.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 干预心脏病学 干预心脏病学
背景情况:
- 对比增强心脏计算机断层扫描 (CT) 越来越多地用于成像左心房尾闭塞 (LAAO) 设备.
- 跨织物泄漏 (TFL) 或在LAAO设备上的对比流可能表明内皮质不完全.
- 关于TFLs的发病率,预测因素和临床影响的数据有限.
研究的目的:
- 确定WATCHMAN FLX左心房附属物阻塞 (LAAO) 装置植入后与跨织物泄漏 (TFLs) 相关的速率,预测因素和临床事件.
- 评估在接受LAAO手术的患者中TFLs的重要性.
主要方法:
- 单中心回顾性队列研究,包括56名接受WATCHMAN FLX LAAO设备和植入后CT扫描的患者.
- 根据TFL的三个拟议定义来对患者进行分类.
- 探索性单变物流回归被用来确定TFL的预测因子.
主要成果:
- 根据所使用的定义,TFL的比例在27%至52%之间.
- 在TFL和没有TFL的组之间没有发现显著的患者或程序差异.
- 没有发现TFL的预测因素;在随访期间发生了6例死亡和1例中风.
结论:
- 在左心房尾闭塞 (LAAO) 程序后,跨织物泄漏 (TFL) 是常见的.
- 人类的完整内皮质化可能与动物模型不同.
- 需要进行进一步的研究,以确定TFL检测的最佳成像,并澄清它们的临床意义.
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