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Updated: Jun 4, 2025

Investigation of the Transcriptional Role of a RUNX1 Intronic Silencer by CRISPR/Cas9 Ribonucleoprotein in Acute Myeloid Leukemia Cells
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Published on: September 1, 2019

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CRTC3限制了SARS-CoV-2的复制,并且受到CREB的对抗

Li Yang1, Xiao-Tao Zeng2, Rong-Hua Luo3

  • 1Department of Pulmonary and Critical Care Medicine, Respiratory Infection and Intervention Laboratory of Frontiers Science Center for Disease-related Molecular Network, and State Key Laboratory of Biotherapy, West China Hospital of Sichuan University, Chengdu 610041, China.

Virologica Sinica
|December 30, 2024
PubMed
概括

主体蛋白CRTC1,CRTC2和CRTC3通过向病毒RNA依赖RNA聚合酶 (RdRp) 来抑制人类冠状病毒 (HCoV) 复制. 这些CRTC为开发新的抗HCoV疗法提供了潜力.

关键词:
由CREB监管的转录协活性剂3 (CRTC3)循环AMP反应元结合蛋白 (CREB) 是一种循环AMP反应元结合蛋白.人类冠状病毒 (HCoVs)依赖RNA的RNA聚合酶 (RdRp) 是一种病毒复制是病毒的复制.病毒与主机的互动

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