伦敦西北部的医疗保健资源使用和与炎症性肠病相关的成本:一项追溯链接数据库研究研究
Zia Ui-Haq1, Luiz Causin2, Tahereh Kamalati1
1Imperial College Health Partners, London, UK.
BMC gastroenterology
|December 30, 2024
概括
活性炎症性肠病 (IBD) 显著增加了医疗保健成本和资源使用. 在性结肠炎 (UC) 和克罗恩氏病中实现和维持缓解.
科学领域:
- 胃肠病学 胃肠病学
- 卫生经济学 卫生经济学
- 现实世界的证据研究研究.
背景情况:
- 炎症性肠病 (IBD) 影响了大量患者群体,其中20-40%对治疗没有反应,导致医疗资源利用率和成本高.
- 对英国国家卫生服务 (NHS) 数据进行了分析,以确定IBD管理的改进领域.
- 使用了伦敦西北部 (2016年3月至2020年3月) 的回顾性,匿名数据,因此该试验没有被注册.
研究的目的:
- 为IBD管理描述性地分析医疗保健数据.
- 探索改善资源使用和与IBD相关的成本的潜在领域.
- 为了比较IBD患者的活跃疾病和缓解状态之间的医疗保健资源使用和成本.
主要方法:
- 从伦敦西北部成人IBD患者的Discover数据集中分析现实世界的数据.
- 平均参观人数和每位患者的初级/二级护理费用的比较.
- 根据疾病状况分层分析:活跃疾病与缓解.
主要成果:
- 这项研究包括7733名患有性结肠炎 (UC),克罗恩病 (CD) 或IBD-undefined的患者.
- 活跃疾病与大多数环境中的医疗保健资源使用量显著增加,与缓解相比,医疗保健总成本更高 (p < 0.0001).
- 住院医院护理是活跃疾病的主要成本驱动因素;在UC和IBD-undefined的缓解中也注意到高的选择性住院费用.
结论:
- 更高的医疗保健资源使用和成本与活跃的IBD有关,强调了早期诱导和维持UC和CD缓解的关键需求.
- 实施更新的治疗策略,如"针对目标进行治疗",可能会产生成本效益.
- 通过抵消生物药物费用,减少住院住院时间,可以实现潜在的成本节约.
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