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vmrseq:单细胞甲基化异质性的概率模型.

Ning Shen1,2, Keegan Korthauer3,4

  • 1Department of Statistics, University of British Columbia, Vancouver, Canada.

Genome biology
|December 30, 2024
PubMed
概括

我们开发了vmrseq,这是一种新的统计方法,可以准确地检测单细胞表观遗传学中的可变甲基化区域 (VMR). 这种工具改善了DNA甲基化数据的分析,揭示了细胞异质性和基因表达链接.

关键词:
通过DNA甲基化.表观遗传的异质性 表观遗传的异质性隐藏的马尔科夫模型单细胞双硫酸盐测序

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