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过敏性鼻炎与埃及患者自身免疫性甲状腺疾病的发展之间的关联
Magdy Mohamed Allam1, Soha Magdy Ahmed2, Dalia Khamis El-Deeb3
1Internal Medicine Department, Endocrinology Division, Alexandria University Student Hospital (AUSH), Alexandria University, Alexandria, Egypt. m_mohamed0902@alexmed.edu.eg.
BMC endocrine disorders
|December 30, 2024
概括
过敏性鼻炎 (AR) 是自身免疫性甲状腺疾病 (AITD) 的风险因素. 被诊断为AR的患者显示AITD的累积发病率较高,建议在AR诊断时对AITD进行查.
科学领域:
- 免疫学 免疫学 免疫学
- 内分泌学 在内分泌学.
背景情况:
- 自身免疫性甲状腺疾病 (AITD) 和过敏性鼻炎 (AR) 是常见的疾病.
- 有限的研究存在于AITD和AR之间的关联.
研究的目的:
- 调查过敏性鼻炎 (AR) 是否是发展自身免疫性甲状腺疾病 (AITD) 的风险因素.
主要方法:
- 从2017年1月到2021年12月,对4515名患者进行了回顾性队列研究.
- 分析包括甲状腺功能测试,抗体,乙素和IgE水平.
- 使用了卡普兰-梅尔分析和多变量调整的危险比率.
主要成果:
- 41.7%的AITD患者也有AR.
- 在AR队列中,AITD的累积发病率明显高 (p=0.001).
- AR,女性性别,白细胞数量升高和11月诊断与AITD风险增加有关.
结论:
- 过敏性鼻炎 (AR) 可能成为自身免疫性甲状腺疾病 (AITD) 的危险因素.
- 在诊断AR时建议对AITD进行查.
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