在初级保健中初始药理性COPD治疗趋势 (2010-2021):使用PHARMO数据网络进行基于人口的研究
Guilherme Rodrigues1,2,3,4, Joana Antão5,6,7,8, Qichen Deng8,9,10
1Lab3R, Respiratory Research and Rehabilitation Laboratory, School of Health Sciences, University of Aveiro (ESSUA), Edifício 30, Agras do Crasto, Campus Universitário de Santiago, 3810-193, Aveiro, Portugal. guilherme.rodrigues@ua.pt.
Respiratory research
|December 30, 2024
概括
在荷兰初级保健中,最初的COPD治疗转向了LABA-LAMA组合,而不是LABA-ICS. 一个显著的百分比的患者在诊断时仍然没有接受呼吸道药物,需要进一步研究.
科学领域:
- 肺部医学 肺部医学
- 药理疗研究 药理疗研究
- 一般的做法一般的做法
背景情况:
- 药物治疗对于治疗慢性阻塞性肺病 (COPD) 至关重要.
- 一般医生 (GPs) 是首要提供COPD护理的提供者.
- 了解初级保健中的处方趋势对于改善患者的治疗结果和确定非最佳实践至关重要.
研究的目的:
- 分析荷兰初级保健中新诊断的COPD患者初始药物治疗的趋势.
- 检查从2010年到2021年的处方模式.
主要方法:
- 一项使用PHARMO GP数据库的重复横截面研究.
- 纳入标准:被诊断患有COPD的40岁以上的个人 (ICPC代码R95).
- 在诊断后90天内使用联点回归对处方药进行的趋势分析.
主要成果:
- 在2010年至2021年期间,LABA-LAMA联合治疗显著增加,从0.6%增加到9.6%.
- 在研究期间,LABA-ICS的处方从17.6%降至8.5%.
- 36.4%的患者在诊断后90天内没有接受呼吸道药物.
结论:
- 在最初的COPD药物治疗中观察到的转变可能反映了新的吸入器引入和不断变化的管理准则.
- 在没有医生处方的呼吸道药物开始治疗的大量患者中,突出了进一步调查的必要性.
- 持续监测处方趋势对于优化初级保健中COPD管理至关重要.
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