使用高级主题建模来生成在骨关节炎中基于偏好指数的域
Ayse Kuspinar1, Eunjung Na2, Stanley Hum3
1School of Rehabilitation Science, Faculty of Health Sciences, McMaster University, 1400 Main St. W., IAHS, Hamilton, ON, Canada. kuspinaa@mcmaster.ca.
Health and quality of life outcomes
|December 30, 2024
概括
这项研究确定了6个关键的生命领域受骨关节炎 (OA) 影响,以开发一个新的与健康相关的生活质量 (HRQL) 指数. 这些发现将为创建以患者为中心的OA结果措施提供信息.
科学领域:
- 风湿病学和健康研究成果研究成果
- 患者报告的结果衡量结果.
- 骨关节炎研究 骨关节炎研究
背景情况:
- 与健康相关的生活质量 (HRQL) 对于评估骨关节炎 (OA) 干预措施至关重要.
- 现有的HRQL措施可能无法完全捕捉到OA的经验.
- 需要一个新的OA特定的基于偏好的指数.
研究的目的:
- 为HRQL创建一个新的OA特定偏好指数的域名.
- 纳入患有关节或膝关节OA的个体的观点.
- 为OA开发一个更相关和以患者为中心的HRQL测量方法.
主要方法:
- 使用了 HRQL 指数的形成性测量模型.
- 包括50岁以上被诊断患有部或膝盖OA的参与者.
- 采用BERTopic和层次主题建模 (自然语言处理) 来分析参与者报告的生活影响.
主要成果:
- 包括102名患有关节/膝关节OA的参与者 (平均年龄64.3岁).
- 确定了影响OA生活质量的六大主题:疼痛,楼梯导航,行走,站立,睡眠和和孙子一起玩.
- 这些主题代表了新的HRQL指数的关键领域.
结论:
- 基于患者的观点,自然语言处理 (Natural Language Processing) 根据患者的观点确定了部和膝关节OA的六个基本HRQL域.
- 这些域构成了新的OA特定HRQL指数的基础.
- 未来的步骤包括对指数的项目生成和偏好诱导.
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