在COVID-19大流行期间出生的婴儿经历了对气道过度响应的敏感性增加
Idit Lachover-Roth1,2, Anat Cohen-Engler1, Yael Furman2,3
1Allergy and Clinical Immunology Unit, Meir Medical Center, Kfar Saba, Israel.
Frontiers in allergy
|December 31, 2024
概括
COVID-19大流行并没有显著改变婴儿中的亚托皮性疾病的流行率. 然而,在限制放松后出生的婴儿显示出更高的呼吸道高反应率.
科学领域:
- 免疫学 免疫学 免疫学
- 儿科 儿科 儿科
- 流行病学 流行病学
背景情况:
- 自20世纪60年代以来,包括喘和食物过敏在内的2型炎症疾病增加了.
- 这是一个很棒的节目,这是一个很棒的节目.
- 在全球范围内,COVID-19大流行导致了卫生措施的增加.
研究的目的:
- 为了比较在COVID-19大流行之前和期间出生的儿童中过敏疾病的患病率.
- 调查与流行病相关的卫生对婴儿过敏疾病发展的影响.
主要方法:
- 在牛奶早期暴露试验中对新生儿的潜在随访,直到12个月大.
- 通过每月的调查,收集有关亚托皮性并发症发展的数据.
- 婴儿根据出生日期对以色列COVID-19封锁相对而言被分类.
主要成果:
- 1,989名婴儿完成了随访;1,086名 (54.5%) 患有至少一种 atop 型疾病.
- 在流行病之前或期间出生的婴儿之间,在亚托皮性并发症患病率上没有显著差异.
- 在限制放松后出生的婴儿显示呼吸道过敏反应的发生率显著更高 (68.9%).
结论:
- 在COVID-19大流行期间,婴儿暴露在增加的卫生条件下并没有显著改变亚托皮性并发症的发展.
- 在疫情限制解除后出生的婴儿中观察到更高的呼吸道高响应率.
- 需要进行更长的随访,以充分了解COVID-19限制对亚托皮性疾病发展的长期影响.
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