咖啡和茶的消费和质瘤风险:对队列研究的元分析
Jinyu Pan1, Chuan Shao1, Hui Tang2
1Department of Neurosurgery, Chongqing General Hospital, Chongqing University, Chongqing, China.
Frontiers in nutrition
|December 31, 2024
概括
这次元分析发现茶饮与质瘤风险之间存在潜在的反向关联,但与咖啡没有联系. 咖啡的证据质量非常低,茶的证据质量也很低,需要进一步研究.
科学领域:
- 流行病学 流行病学
- 营养流行病学 营养流行病学
- 在瘤学瘤学.
背景情况:
- 与咖啡和茶饮食的结质瘤风险相关性尚未得到充分证实.
- 以前的研究结果是不确定的,需要进一步调查.
研究的目的:
- 进行一项元分析,研究咖啡和茶的摄入量与质瘤风险之间的关系.
- 评估剂量反应相关性,评估证据质量.
主要方法:
- 在PubMed,Embase和Scopus的系统文献搜索相关的队列研究.
- 包括调整相对风险估计或危险比率 (HRs) 和95%置信区间 (CI) 的研究.
- 使用纽卡斯尔-太华尺度进行质量评估,根据GRADE系统进行证据分级;通过元回归进行剂量反应分析.
主要成果:
- 分析了9项研究 (2004-2020年) 涉及2,648,468名参与者和3,896例质瘤病例.
- 聚合HRs (95%CI) 的最高和最低的消费是0.98 (0.87-1.09) 咖啡和0.95 (0.86-1.06) 茶.
- 剂量反应分析表明,茶的"L"形曲线,风险降低高达2.5杯/天;证据质量是"非常低"的咖啡和"低"的茶.
结论:
- 分析表明,茶饮和质瘤风险之间存在潜在的反向关联,但咖啡并非如此.
- 咖啡和茶的证据质量低,需要谨慎解释.
- 需要进一步的研究来证实这些发现,并阐明饮料消费与质瘤之间的关系.
相关概念视频
02:59Cancer Prevention
6.0K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.0K
01:21Cancer Survival Analysis
290
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
290