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Updated: May 7, 2025

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
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单细胞转录组学揭示了急性髓性白血病中髓性前体细胞的异质性和预后标志物

Guangfeng He1, Lai Jiang2, Xuancheng Zhou2

  • 1Department of Hematology, Affiliated Hospital of Southwest Medical University, Luzhou, China.

Frontiers in immunology
|December 31, 2024
PubMed
概括

研究人员确定了八个关键基因,以改善急性髓性白血病 (AML) 的预后. 这一发现为个性化AML治疗提供了潜在的新生物标志物和治疗点.

关键词:
急性骨髓性白血病 (AML) 是一种急性骨髓性白血病.免疫系统的逃脱是免疫逃脱.免疫疗法 免疫疗法个性化治疗 个性化治疗预后生物标志物 预后生物标志物

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Common myeloid progenitors (CMPs) are oligopotent cells that can differentiate into granulocytes and macrophages. Granulocytes and macrophages are essential for protecting the body against bacterial, viral, or fungal infections. They migrate from the bone marrow into the circulating blood to reach specific tissue sites where they differentiate and help in immune surveillance. However, they survive only for a few days and must be continuously made available to the organism to maintain a robust...
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