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结节的特征及其与乳头甲状腺癌的相关性:一个横截面研究

Meng Wang¹, Shaogang Ma², Guangwei Jiang³

¹Department of Endocrinology and Metabolism, Linping Campus, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, CHN.

|December 31, 2024

概括

结节性喉 (NG) 在甲状腺手术中很常见,并且显著增加了乳头甲状腺癌 (PTC) 的风险. 甲状腺刺激激素 (TSH) 和癌胚抗原 (CEA) 水平的升高与NG患者的PTC有关.

科学领域:

内分泌学在内分泌学.
在瘤学瘤学.
手术病理学手术病理学

背景情况:

结节性喉 (NG) 是一种常见的甲状腺疾病.
NG与乳头甲状腺癌 (PTC) 之间的关联需要进一步调查.
了解NG的临床特征对于治疗甲状腺疾病至关重要.

研究的目的:

为了研究结节性喉 (NG) 的临床特征.
确定结节性喉 (NG) 和乳头性甲状腺癌 (PTC) 之间的关系.
在NG患者中确定与PTC相关的潜在生物标志物.

主要方法:

对282名因怀疑甲状腺癌而接受甲状腺手术的患者的回顾性分析.
实验室检测,超声波和病理学数据的比较,用和没有NG的患者之间.
统计分析以评估临床特征和结果差异的意义.

主要成果:

结节性喉 (NG) 在48.9%的患者中存在.
与没有NG的患者相比,NG患者的PTC (23.2%) 和出血率 (29.0%) 较高 (p < 0.001).
甲状腺刺激激素 (TSH) 和癌胚抗原 (CEA) 水平的升高在PTC患者中显著更高,特别是那些NG患者 (p < 0.001).

结论:

结节性喉 (NG) 在接受甲状腺手术的患者中非常普遍.
NG与患乳头甲状腺癌 (PTC) 的风险增加有关.
提升的TSH和CEA水平可能作为NG患者PTC的指标,需要进一步的临床关注.

关键词:

癌症生物标志物癌症生物标志物临床分析临床分析结节性肠炎是什么意思皮囊甲状腺癌是甲状腺癌.甲状腺刺激激素激素激发甲状腺刺激激素.

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