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为了设计更好的癌症免疫治疗点,使用-MHC-I呈现模型,HLApollo

William John Thrift1, Nicolas W Lounsbury2, Quade Broadwell1

  • 1Early Clinical Development Artificial Intelligence, Genentech, South San Francisco, CA, USA.

Nature communications
|December 31, 2024
PubMed
概括

新型变压器模型HLApollo准确地预测了个性化癌症疫苗的MHC-I呈现. 它通过分析和MHC序列来改进现有方法,帮助癌症免疫疗法开发.

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