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Updated: Jun 4, 2025

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乳牛相关的H5N1病毒中的单一突变增加了受体结合宽度

Marina R Good1, Monica L Fernández-Quintero2, Wei Ji1

  • 1Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Nature communications
|December 31, 2024
PubMed
概括

最近在美国奶牛中发现的H5N1禽流感病毒对鸟类受体的结合性增加. 一种突变 (T199I) 增强了受体结合部位的灵活性,可能扩大了H5N1的宿主范围.

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