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在人类大脑中检测真菌序列:rDNA位置放大和深度测序

Rodrigo Leitao1, Iam Ut Wan2, Harry Chown2

  • 1MRC Centre for Global Infectious Disease Analysis, School of Public Health, Imperial College London, London, W12 0BZ, UK. r.monteirinho-leitao@imperial.ac.uk.

Scientific reports
|December 31, 2024
PubMed
概括

真菌感染可能在神经退行性疾病中发挥作用,例如阿尔茨海默病 (AD) 和帕金森病 (PD). 研究人员使用纳米孔测序来检测脑组织和脑脊液 (CSF) 中的真菌DNA.

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RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
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