症状和重重度之间的关系在初级额头气:心血管磁共振研究研究
Seth Uretsky1, SakulSakul2, Jonathan Igancio3
1Department of Cardiovascular Medicine, Gagnon Cardiovascular Institute, Morristown Medical Center/Atlantic Health System, 100 Madison Ave, Morristown, NJ, 07960, USA. seth.uretsky@atlantichealth.org.
额头肌反 (MR) 的症状并不总是与MR的严重程度有关. 一项研究发现,MR体积 (MRV) 和MR分数 (MRF) 之间的关系比单独的MRV更好地预测症状,这表明其他因素可能导致症状.
科学领域:
- 心脏病学 心脏病学
- 心血管成像 - 心血管成像
- 医学诊断 医学诊断 医学诊断
背景情况:
- 目前的ACC/AHA指导方针强调在初级额头肌吐 (MR) 中进行手术时机的症状存在.
- 在MR的严重程度和患者报告的症状之间存在显著的脱节.
- 了解影响症状的因素对于准确的患者管理至关重要.
研究的目的:
- 为了确定诊断为慢性初级额头肌吐的患者症状的危险因素.
- 调查MR严重程度指标和症状患病率之间的关系.
主要方法:
- 利用心血管磁共振 (CMR) 成像在430名患有退行性MR和保存左心室功能的患者中.
- 根据ACC/AHA指南使用MR体积 (MRV) 和MR分数 (MRF) 分类MR严重程度.
- 分析了MRV和MRF相对类别 (V>F,V=F,V
主要成果:
- 没有观察到与MRV严重程度恶化的症状患病率显著增加 (p=0.4).
- 在严重的MRF (p=0.054) 中,人们注意到症状增加的趋势.
- 与V
- 多变量分析确定了年龄,女性性别,MRF和V
- 多变量分析确定了年龄,女性性别,MRF和V
结论:
- 退行性MR中症状的存在与MR体积的增加无关.
- MRV 和 MRF (V
- 研究结果表明,其他潜在病理可能导致MR患者的症状,需要进一步调查.
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