子宫内膜切除或切除与levonorgestrel宫内器械结合后对出血模式的长期影响
Signe Engholm Straarup1,2, Ina Isabell Kathleen Heinemeier1,2, Pernille Darre Haahr1,2
1Department of Obstetrics and Gynecology, Odense University Hospital, Kløvervænget 23, 5000, Odense, Denmark.
添加莱诺格斯特勒子宫内置器 (LNG-IUD) 显著改善了子宫内膜切除 (TCRE) 后异常子宫出血的异常异常异常异常异常异常异常异常异常. 当LNG-IUD与NovaSure子宫内膜切除相结合时,没有显著的益处.
科学领域:
- 妇科 妇科 妇科 妇科
- 最少侵入性的手术
- 生殖医学 生殖医学
背景情况:
- 异常子宫出血 (AUB) 影响了许多女性,并经常通过子宫内膜切除或切除进行治疗.
- 这些手术可能有很高的复手率,需要改进治疗策略.
- 结合手术和levonorgestrel子宫内置器械 (LNG-IUD) 正在探索,以提高结果.
研究的目的:
- 为了评估AUB的子宫内膜切除 (TCRE) 或切除 (NovaSure) 后的12个月异常发病率.
- 评估立即将这些程序与LNG-IUD相结合对异常发病率的影响.
主要方法:
- 一项前性队列研究,涉及119名接受AUB治疗的妇女.
- 在手术后12个月,通过关于出血模式的问卷收集数据.
- 统计分析,以比较不同治疗组之间的异常发病率.
主要成果:
- 单独使用TCRE的亚美诺雷亚率为11%,而使用TCRE+LNG-IUD的比例为58% (p=0.008).
- 对于NovaSure,单独使用时,杏仁病发病率为48%,使用NovaSure + LNG-IUD时为62% (p=0.744).
- 结合LNG-IUD在TCRE后显著增加了缺血,但在NovaSure后没有.
结论:
- 通过子宫切除子宫内膜 (TCRE) 单独对实现异常流产的效果有限.
- 将TCRE与LNG-IUD相结合,显著提高了异常发病率,使其与NovaSure相比较.
- 将LNG-IUD添加到NovaSure废除过程中,并没有显著改善异常发病率.
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