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Updated: May 11, 2026

Sagittal Plane Kinematic Gait Analysis in C57BL/6 Mice Subjected to MOG35-55 Induced Experimental Autoimmune Encephalomyelitis
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被破坏的状连接是NMDA受体抗体脑炎小鼠模型中长期存在的感觉运动缺陷的基础

Jing Zhou1,2,3, Ariele L Greenfield1,2, Rita P Loudermilk1,2

  • 1Department of Neurology.

The Journal of clinical investigation
|December 31, 2024
PubMed
概括

早期接触N-甲基-D-酸盐 (NMDA) 受体抗体会通过改变大脑连接在小鼠中引起持久的感觉运动缺陷. 这项研究揭示了NMDAR-AE.在NMDAR-AE.在持续的神经问题潜在的机制.

关键词:
这是一种自身免疫力.鼠标模型 鼠标模型神经系统疾病 神经系统疾病神经科学是一个神经科学.

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Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...