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胆固醇黄的婴儿血清维生素D状况
S A Biswas1, M Rukunuzzaman, R K Biswas
1Dr Subir Ananda Biswas, Resident, Department of Paediatric Gastroenterology & Nutrition, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh;
Mymensingh medical journal : MMJ
|December 31, 2024
概括
患有胆固醇黄的婴儿经常缺乏维生素D,其中43.3%的患者表现出低水平. 这凸显了在被诊断患有胆固醇病的婴儿中对维生素D的监测和补充的关键需求.
科学领域:
- 儿科胃肠道学和营养学
- 肝病学 肝病学是一种肝病学.
- 内分泌学 在内分泌学.
背景情况:
- 婴儿的胆固醇黄会导致脂肪溶性维生素缺乏.
- 维生素D缺乏是儿科胆固醇病的常见和重大挑战.
- 早期诊断和治疗胆固醇黄对于预防并发症至关重要.
研究的目的:
- 评估被诊断患有胆固醇黄的婴儿的血清25-基维生素D状态.
- 为了比较患有胆固醇黄的婴儿和健康对照的婴儿之间的维生素D水平.
- 调查胆固醇的婴儿维生素D水平和临床参数之间的相关性.
主要方法:
- 一项横截面分析研究,涉及30名患有胆固醇黄的婴儿和30名对照.
- 病例包括标准:三个月前黄,特定胆红素水平,白的便和深色的尿液.
- 在病例和对照中测量血清25-氧维生素D,血清和肝脏生物化学.
主要成果:
- 与对照组 (27.68 ng/ml) 相比,患有胆固醇黄的婴儿的血清25-基维生素D水平 (14.7 ng/ml) 的平均值显著降低.
- 在43.3%患有胆固醇黄的婴儿中观察到维生素D缺乏 (<15 ng/ml).
- 在血清25-基维生素D和胺转化酶 (GGT) 之间发现了显著的负相关性,以及与血清的积极相关性.
结论:
- 患有胆固醇黄的婴儿显示血清25-氧维生素D水平显著降低.
- 在这个儿科群体中,维生素D缺乏是普遍存在的.
- 常规监测和适当的维生素D补充对于患有胆固醇黄的婴儿至关重要.
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