血液培养采集包对降低污染率的影响
Miki Doi1, Yoshio Takesue2,3, Miyuki Makino3
1Department of Clinical Technology, Tokoname City Hospital, Tokoname, Aichi, Japan.
PloS one
|December 31, 2024
概括
采用捆绑式的血液采集方法显著降低了血液培养污染率. 这一策略涉及特定的皮肤制备和无菌转移装置,使污染率从2.0%降至1.0%.
科学领域:
- 临床微生物学 临床微生物学
- 传染性疾病 传染性疾病
- 患者安全 患者安全
背景情况:
- 血液培养物的污染是临床微生物学中持续存在的挑战.
- 污染的血液培养可以导致不必要的抗生素使用和长时间住院.
- 目前采集血液的方法可能无法充分防止微生物污染.
研究的目的:
- 评估捆绑方法在降低血培污染率方面的有效性.
- 评估具体干预措施对污染生物发生率的影响.
- 确定捆绑方法是否能减轻污染的季节性变化.
主要方法:
- 实施了一种包装方法,包括静脉穿刺,醇皮肤制备,消毒培养瓶和无菌输血装置.
- 污染被定义为来自单一血组的共生生物,在72小时内没有第二组阳性.
- 对照期3年与干预期2年进行了比较.
主要成果:
- 整体血液培养污染率在捆绑实施后显著下降,从2.0%降至1.0% (p<0.001).
- 观察到凝固酶阴性葡萄球菌污染的显著减少 (p<0.001).
- 在干预期间,污染的季节性增加,特别是夏季的细菌物种,被消除了.
结论:
- 收集血液的捆绑方法在减少血液培养污染方面非常有效.
- 干预成功降低了常见污染物的比率,如凝结酶阴性葡萄球菌.
- 捆绑战略还解决并消除了污染率的季节性波动.
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