肺癌手术中与Clavien-Dindo并发症相关的预测因素:一个回顾性队列研究
Mantana Saetang1, Thitikan Kunapaisal1, Wirat Wasinwong1
1Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University, Hat-Yai, Songkhla, Thailand.
PloS one
|December 31, 2024
概括
接受手术的老年肺癌患者面临心肺并发症的重大风险. 诸如COPD和肺切除术等因素增加了这些风险,需要进行全面的风险评估以获得更好的结果.
科学领域:
- 胸部外科手术 胸部外科手术
- 老年瘤学 老年瘤学
- 肺部医学 肺部医学
背景情况:
- 老年患者的肺癌手术对术后心肺并发症的风险很高.
- 克拉维恩 - 丁多 (CD) 分类系统用于对外科并发症的严重程度进行分级.
研究的目的:
- 在接受肺癌手术的老年患者中识别术后心肺并发症 (Clavien-Dindo等级≥II) 的危险因素.
- 评估风险评估工具对这些并发症的有用性.
主要方法:
- 对239名老年患者 (≥60岁) 的回顾性分析,这些患者在2020-2023年期间接受了肺癌手术.
- 后勤回归和接收器运行特征 (ROC) 曲线被用来分析CD等级≥II并发症的风险因素.
主要成果:
- 29.3%的患者经历了术后并发症 (CD ≥II).
- 对于CD等级≥II并发症的独立预测因素包括老年 (OR: 1.08),COPD (OR: 4.41),吸烟史 (OR: 2.85),肺切除术 (OR: 14.89),以及转换为胸切除术 (OR: 16.33).
- ROC曲线显示出良好的预测准确性 (曲线下的面积=0.81).
结论:
- 虽然年龄较大 (≥70) 显示出并发症增加的趋势,但这不是一个独立的预测因素.
- 慢性肺炎,肺切除术和转换为胸切除术是严重的术后并发症的重要危险因素.
- 多因素风险评估对于优化术后管理和改善该患者群体的结果至关重要.
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