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Updated: Jun 4, 2025

Induction and Validation of Cellular Senescence in Primary Human Cells
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通过整合转录基因数据识别的衰老细胞中DNA修复基因的广泛抑制

Yann Frey1,2, Majd Haj1,2, Yael Ziv1,2

  • 1The David and Inez Myers Laboratory for Cancer Research, Tel Aviv University, Tel Aviv 6997801, Israel.

Nucleic acids research
|December 31, 2024
PubMed
概括

衰老细胞表现出减少的DNA修复基因表达,表明DNA损伤累积. 衰老细胞的修复能力受损可能会导致衰老和癌症复发.

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