超越发作:患有的儿童的精神病并发症
Dana Ayoub1, Amal Al-Hajje2, Pascale Salameh3
1Inserm U1094, IRD U270, Univ. Limoges, CHU Limoges, EpiMaCT - Epidemiology of Chronic Diseases in Tropical Zone, Institute of Epidemiology and Tropical Neurology, OmegaHealth, Limoges, France; Clinical and Epidemiological Research Laboratory, Faculty of Pharmacy, Lebanese University, Beirut, Lebanon; School of Pharmacy, Lebanese International University, Beirut, Lebanon.
精神疾病影响了黎巴嫩12.5%的儿童,外化疾病在发育迟缓的儿童中更为常见. 发作控制不良和发作时年龄较大与内化障碍有关.
科学领域:
- 儿科神经学 儿科神经学
- 儿童精神病学 儿童精神病学
- 流行病学 流行病学
背景情况:
- 患有的儿童面临更高的精神病并发症风险,这可能会使他们的病情恶化.
- 在发展中国家,这些并发症往往被低诊断和低报告.
研究的目的:
- 为了确定在黎巴嫩的一大批患有的儿童中精神疾病的频率.
- 在这个人群中确定与精神病相关疾病相关的因素.
主要方法:
- 在黎巴嫩 (2010-2016年) 对598名患有新发作的儿童进行前性队列研究.
- 基于DSM-5标准的精神疾病 (内部化/外部化) 医疗记录分析.
- 多变量逻辑回归用于识别相关因素.
主要成果:
- 12.5%的儿童 (75/598) 被诊断出患有精神疾病:5.0%内化和7.9%外化.
- 在发育性性脑病变中,外部化障碍最常见 (18.2%);智力/发育迟缓是一个关键因素 (OR 3.36).
- 内化障碍与≥2种抗发作药物 (OR 3.25) 和发作发作时的年龄 (OR 6.86) 的失败有关.
结论:
- 诊断出精神伴随性疾病的患病率低于发达国家,这表明黎巴嫩的潜在报告不足.
- 在例行访问期间,系统的精神病学查至关重要,特别是对于发育迟缓或控制不良的儿童.
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