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Updated: Jun 4, 2025

Assaying Circuit Specific Regulation of Adult Hippocampal Neural Precursor Cells
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Assaying Circuit Specific Regulation of Adult Hippocampal Neural Precursor Cells

Published on: July 24, 2019

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循环AMP调节的承诺可以恢复神经发育障碍患者的认知功能

Aniket Bhattacharya1, Luka Turkalj1, M Chiara Manzini1

  • 1Department of Neuroscience and Cell Biology and Child Health Institute of New Jersey, Rutgers Robert Wood Johnson Medical School, New Brunswick, 08901, USA.

Current opinion in neurobiology
|December 31, 2024
PubMed
概括

向二酶4D (PDE4D) 的选择性抑制剂通过恢复认知功能来治疗神经发育和神经退行性疾病具有前景. 这些新型化合物提供了更好的选择性和生理抑制,促进了治疗的发展.

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Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs

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Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
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